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K502

In cats, the growth and structure of coat hairs is partially governed by the gene for lysophosphatidic acid receptor 6 (LPAR6).

Working days 10

Specifications

Breeds

,

Gene

Organ

specimen

Swab, Blood EDTA, Blood Heparin, Semen, Tissue

Mode of Inheritance

Chromosome

Year Published

General information

In cats, the growth and structure of coat hairs is partially governed by the gene for lysophosphatidic acid receptor 6 (LPAR6). A recessive mutation to this gene is responsible for the distinctive curly coat of the Cornish Rex breed.

Clinical features

Affected cats develop fur without guard hairs and awn hairs, which normally form the outer layers of a coat. Instead, their coat is exclusively made up of down hairs, which are extremely fine and naturally wavy or curly, typically falling in washboard-like waves. As these hairs are relatively thin and fragile, affected cats are somewhat prone to developing bald patches, and are more sensitive to cold temperatures than other cats.

Extra information

References

Pubmed ID: 23826204

Omia ID: 1684

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3. Results

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