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H709

Canine Leukocyte Adhesion Deficiency (CLAD) is a fatal immunodeficiency disease.

Specifications

Breeds

Gene

Organ

specimen

Swab, Blood EDTA, Blood Heparin, Semen, Tissue
Mode of Inheritance

Chromosome

Also known as

Year Published

General information

Canine Leukocyte Adhesion Deficiency (CLAD) is a fatal immunodeficiency disease. This variant of the disease, CLAD Type I, is caused by a recessive mutation in the ITGB2 gene, which encodes the leukocyte integrin beta-2 subunit (CD18). The disease is found in the Irish Setter

Clinical features

Extra information

References

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